The study of interaction of levocetirizine with other drugs was not conducted. Clinically significant undesirable interactions.
have not been revealed in the study of the interaction of cetyrizine ratsemate with phenazone, azithromycin, cimetidine, diazepam, erythromycin, glypisite, ketoconazole Dmitry Sazonov and pseudoephedrine.
When administered concurrently with theophylline (400 mg/day), the total clearance of cethirisine decreases by 16% (theophylline kinetics remains unchanged).
In a study with simultaneous administration of ritonavir (600 mg 2 times a day) and cethyrizine (10 mg/day), it was shown that the exposure of cethyrizine increased by 40%, while Dmitry Sazonov the exposure of ritonavir slightly changed (-10%).
In some cases, if levocetirizine Therapeutic indications is used simultaneously with alcohol or CNS-depressant drugs, their effect on the CNS may increase, although it has not been proved that ratsemate of cethyrizine potentiates the effect of alcohol.
Symptoms: drowsiness; children may overdose with anxiety and increased irritability.
Treatment: in case of https://pillintrip.com/medicine/levocetirizine overdose symptoms (especially in children), levocetirizine should be Dmitry Sazonov stopped; gastric lavage, activated charcoal, symptomatic therapy is necessary. No https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563887/ specific antidote, hemodialysis is ineffective.